1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-101476R
    Emodepside (Standard)
    Inhibitor
    Emodepside (Standard) is the analytical standard of Emodepside. This product is intended for research and analytical applications. Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.
    Emodepside (Standard)
  • HY-B2138R
    Ethopabate (Standard)
    Inhibitor
    Ethopabate (Standard) is the analytical standard of Ethopabate (HY-B2138). This product is intended for research and analytical applications. Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    Ethopabate (Standard)
  • HY-151150
    Trypanothione synthetase-IN-2
    Trypanothione synthetase-IN-2 (Compound 3) is a competitive Leishmania infantum trypanothione synthetase (TryS) inhibitor with an IC50 of 5.4 μM when triamine spermidine is as polyamine S.
    Trypanothione synthetase-IN-2
  • HY-136081
    Hexamidine
    Inhibitor
    Hexamidine has amoebicidal effect that can be used for the research of Acanthamoeba keratitis.
    Hexamidine
  • HY-12404R
    Diminazene (aceturate) (Standard)
    Inhibitor
    Diminazene (aceturate) (Standard) is the analytical standard of Diminazene (aceturate). This product is intended for research and analytical applications. Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.
    Diminazene (aceturate) (Standard)
  • HY-117146
    Indoxacarb
    Indoxacarb ((S)-DPX-JW062) is an oxathiazole insecticide with activity against a wide range of insect pests. Indoxacarb is used in forest pest management to control insect pests, and its toxicity has significant effects on adult individuals of the predatory stink bug Podisus distinctus. Indoxacarb showed high toxicity to P. distinctus at a lethal concentration (LC50 = 2.62 g L-1). Indoxacarb treatment significantly reduced the survival rate of P. distinctus, with the survival rate of individuals exposed to 2.62 g L-1 decreasing to 40.7%. Indoxacarb also reduced the respiration rate of P. distinctus from 18.45 to 14.41 μL CO2 h-1, and inhibited its food intake. P. distinctus showed hyperexcitatory responses after Indoxacarb treatment.
    Indoxacarb
  • HY-168959
    Antiparasitic agent-25
    Inhibitor
    Antiparasitic agent-25 (Compounds 11) is an orally active antiparasitic agent. Antiparasitic agent-25 inhibits both parasite invasion and replication ability and has irreversible action against Toxoplasma gondii, significantly reducing the replication rate of Toxoplasma gondii with an IC50 value of 6.33 μM, and demonstrates low cytotoxicity with a CC50 value of 285 μM.
    Antiparasitic agent-25
  • HY-N10544
    δ-Cadinene
    Inhibitor
    δ-Cadinene ((+)-δ-Cadinene) is a sesquiterpene in essential oils. δ-Cadinene shows antiproliferative and pro-apoptotic effects on human ovary cancer (OVCAR-3) cells. δ-Cadinene has trichomonacidal, antimicrobial, antifungal and anticancer properties.
    δ-Cadinene
  • HY-115584B
    Lufenuron, (-)-
    Inhibitor
    Lufenuron, (-)- is an active isomer form of Lufenuron. Lufenuron is a lipophilic benzoyl urea insecticide and chitin synthesis inhibitor that can be used for flea and fish lice control. Lufenuron inhibits the molting of arthropods.
    Lufenuron, (-)-
  • HY-12361R
    PF 1022A (Standard)
    Inhibitor
    PF 1022A (Standard) is the analytical standard of PF 1022A. This product is intended for research and analytical applications. PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against Ascaridia galli in chickens. PF 1022A also can be used for angiostrongyliasis research[1][2][3].
    PF 1022A (Standard)
  • HY-118896R
    Acequinocyl (Standard)
    Acequinocyl (Standard) is the analytical standard of Acequinocyl. This product is intended for research and analytical applications. Acequinocyl (CRM) is a certified reference material categorized as a naphthoquinone acaricide.1 Acequinocyl has been found in Cannabis. Formulations containing acequinocyl have been used to control mite populations in agriculture. This product is intended for research and forensic applications.
    Acequinocyl (Standard)
  • HY-113562
    Laidlomycin phenylcarbamate
    Inhibitor
    Laidlomycin phenylcarbamate is a semisynthetic polyether antibiotic with antiparasitic activity.
    Laidlomycin phenylcarbamate
  • HY-N14242
    Jietacin B
    Inhibitor
    Jietacin B is found to be resistant to nematode, it can kill Burs helenchus Lignicolus with the concentration of 0.25 μg/mL.
    Jietacin B
  • HY-158364
    NMT-IN-3
    Inhibitor
    NMT-IN-3 is an inhibitor of N-myristoyltransferase (NMT). The IC50 of NMT-IN-3 for Plasmodium vivax NMT is 38 mM.
    NMT-IN-3
  • HY-116433R
    Nequinate (Standard)
    Inhibitor
    Nequinate (Standard) is the analytical standard of Nequinate. This product is intended for research and analytical applications. Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections. Nequinate inhibits xanthine oxidoreductase (XOD) activity.
    Nequinate (Standard)
  • HY-N6961R
    Lapachol (Standard)
    Inhibitor
    Lapachol (Standard) is the analytical standard of Lapachol. This product is intended for research and analytical applications. Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity.
    Lapachol (Standard)
  • HY-168547S
    AR89-d6
    Inhibitor
    AR89-d6 (Compound AR102) is a deuterated derivative of AR89 with oral activity. AR89-d6 demonstrates activity against S. mansoni, S. haematobium, and S. japonicum, and can be utilized for research on schistosomiasis.
    AR89-d<sub>6</sub>
  • HY-N0078R
    Ginkgolic Acid (C13:0) (Standard)
    Inhibitor
    Ginkgolic Acid (C13:0) (Standard) is the analytical standard of Ginkgolic Acid (C13:0) (HY-N0078). This product is intended for research and analytical applications. Ginkgolic Acid (C13:0) (Ginkgoneolic Acid) is an anti-cariogenic agent and a PI3Kδ inhibitor (IC50: 2.49 μM). Ginkgolic Acid (C13:0) exhibits antibacterial and anti-parasitic activities. Ginkgolic Acid (C13:0) can also inhibit mast cell degranulation (IC50: 2.40 μM).
    Ginkgolic Acid (C13:0) (Standard)
  • HY-116736
    BRD7539
    Inhibitor
    BRD7539 is a PfDHODH inhibitor (IC50 = 0.033 μM). BRD7539 has potent activity against both multidrug-resistant asexual blood-stage (P. falciparum, Dd2 strain, EC50 = 0.010 μM) and liver-stage (P. berghei, EC50 = 0.015 μM) parasites.
    BRD7539
  • HY-W098008
    Fenbendazole analog-1
    Inhibitor
    Fenbendazole analog-1 (compound 9) is a 2-methoxycarbonylamino-derived antiparasitic compound and inhibits rat brain tubulin polymerization. Fenbendazole analog-1 inhibits the growth of the protozoa Giardia lamblia, Entamoeba histolytica, and the worm Trichinella spiralis.
    Fenbendazole analog-1

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